NMDAR antagonist 1 ( —— )

产品货号. M20173 CAS No. 2220162-06-9

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产品名称

NMDAR antagonist 1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

NMDAR Antagonist 1 是一种有效的、口服生物可利用的 NR2B 选择性 NMDAR 拮抗剂。
产品描述

NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective antagonist of NMDAR.
体外实验

NMDAR antagonist 1 (Compound 5q) exhibits excellent neuroprotective activity. NMDAR antagonist 1 can attenuate Ca2+ influx induced by NMDA.NMDAR antagonist 1 can suppress the NR2B up-regulation and increase p-ERK1/2 expression.NMDAR antagonist 1 inhibits SH-SY5Y cells with cell viabilities of 75.8%, 80.0%, 84.4%, and 78.6% at 0.1 μM 1 μM 10 μM 100 μM, respectively.
体内实验

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